Disable Auto Play

Put the following in a registry file and execute it to disable AutoPlay on all drives
See more details here

Windows Registry Editor Version 5.00

[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\policies\Explorer]
"NoDriveTypeAutoRun"=dword:000000ff

You can selectively drives with the following values (that can be 'Or'ed together)

Value Meaning
0x1 Disables AutoPlay on drives of unknown type
0x4 Disables AutoPlay on removable drives
0x8 Disables AutoPlay on fixed drives
0x10 Disables AutoPlay on network drives
0x20 Disables AutoPlay on CD-ROM drives
0x40 Disables AutoPlay on RAM disks
0x80 Disables AutoPlay on drives of unknown type
0xFF Disables AutoPlay on all kinds of drives